Filmis mängivad peaosi Uma Thurman, Lucy Liu, Vivica A. Fox, Michael Madsen, Darryl Hannah ja David Carradine (kes on Bill).
Uma Thurman kehastab rasedat palgamõrvarit, keda tema pulmapäeval tulistab Bill. Ta lebab viis aastat koomas ja kui ta üles ärkab, algab klaperjaht Billile.
“Kill Billi” muusikavalik on alljärgnev:
“Bang Bang (My Baby Shot Me Down)” — Nancy Sinatra
“That Certain Female“ — Charlie Feathers
“The Grand Duel — (Parte Prima)“ — Luis Bacalov
“Twisted Nerve“ — Bernard Herrmann
Queen Of The Crime Council — dialoogikatked filmist, kus esinevad Lucy Liu
ja Julie Dreyfus
“Ode To Oren Ishii“ — The RZA
“Run Fay Run“ — Isaac Hayes
“Green Hornet“ — Al Hirt
“Battle Without Honor or Humanity“ — Tomoyasu Hotei
“Don’t Let Me Be Misunderstood“ — Santa Esmeralda
“Woo Hoo“ — The 5.6.7.8’s
“Crane”/“White Lightning“ — The RZA/Charles Bernstein
“The Flower of Carnage“ — Meiko Kaji
“The Lonely Shepherd“ — Zamfir
You’re My Wicked Life — dialoogikatked David Carradine´i, Julie Dreyfusi ja
Uma Thurmaniga
“Ironside” — Quincy Jones
“Super 16“ — Neu!
Kung Fu Stings ja SFX
